Shi Lab at UNC Charlotte is a computational systems biology lab, focusing on the design and development of tools and algorithms to solve large-scale computational problems in biomedical research and big data health. Specifically, we are developing computational approaches/pipelines to integrate and analyze large-scale (epi)genomic, expression, interaction, language, and cultural data sets to investigate complex diseases and infectious diseases. We are also developing techniques to preserve genetic privacy in human genomic data.

Research Areas

  • Machine Learning
  • Genomic Privacy and Security
  • Multi-omics Data Integration
  • Network Science
  • Epistasis Analysis
  • Quantitative Trait Loci (QTL) Mapping
  • Genome Wide Association Studies
  • Genetic Variation (e.g. Structural Variation)
  • Big Data Health